• National Technology Centre for Ports, Waterways and Coasts (NTCPWC)
• Robert Bosch Center for Data Science and Artificial Intelligence
• Centre of Excellence on Dam Safety & Dam Rehabilitation
• Centre of Excellence (CoE) in Advanced Materials and Manufacturing
• Centre of Propulsion Technology (CoPT)
• Graphene Applications (TSAMRC)
• The Centre for Excellence in Steel Technology (CoExiST)
• Industrial Internet of Things (IIT-GE)
• for Urbanization, Buildings and the Environment (CUBE)
• Applied Centre for Advanced Automotive Research (CAAR)
• Indian Solar Energy Harnessing Centre (ISEHC)
• Raghupathi Singhania Centre of Excellence for Tyre & Vehicle Mechanics
• Centre of Excellence in Urban Transport
• Centre of Decentralised Power Systems
• Centre for Non-Destructive Evaluation
• National Centre for Combustion R&D
• National Centre for Catalysis Research
• Centre for NEMS & Nanophotonics (CNNP)
• Healthcare Technology Innovation Centre( HTIC)
• Centre for Technology and Policy (CTaP)
• National Centre for Safety of Heritage Structures (NCSHS)
• Indo-German Centre for Sustainability (IGCS)
• China Studies Centre
• Reliance-IITM Telecom Centre of Excellence
• Centre for Functional Nanomaterials
• Thematic Unit of Excellence on Water
• Centre for Excellence in Wireless Technology (CEWIT)
• Centre of Excellence on Machine Tools and Production Technology (AMTDC)
• Centre of Excellence in Iron & Steel Technology (COEXIST)
• Centre for Computational Brain Research (CCBR)
• Interdisciplinary Laboratory in Data Sciences (ILDS)
• Initiative in Biological Systems Engineering (IBSE)
• Centre for Social Innovation & Entrepreneurship (CSIE)
• Centre for Railway Research (CRR)
• Centre for Battery Engineering and Electric Vehicles (CBEEV)
• TTK Centre for Rehabilitation Research and Device Development (R2D2)
• Thematic Unit of Excellence (TUE) on Water Purification using Nanotechnology